Overview

Effect of an Antioxidant on Cancer-Cachectic Patients Undergoing Exercise Training

Status:
Completed
Trial end date:
2006-12-01
Target enrollment:
0
Participant gender:
All
Summary
The purpose of the study is to tests the hypothesis, that N-acetylcysteine (a thiol-antioxidant)improves the exercise training effect on cancer patients that experience weight loss (cachexia) as assessed by muscle mass and function as well as histomorphology.
Phase:
Phase 2
Accepts Healthy Volunteers?
Accepts Healthy Volunteers
Details
Lead Sponsor:
German Cancer Research Center
Collaborator:
Heidelberg University
Treatments:
Acetylcysteine
N-monoacetylcystine
Criteria
Inclusion Criteria:

- gastrointestinal or bronchial cancer

- weight loss of 10% within 6 months

- sufficient mobility

Exclusion Criteria:

- severe pain, steroid therapy, severe internal, muscular, neurological, psychiatric
disease, N-acetylcysteine allergy