Effect of Weight and/or Obesity on Ethambutol Drug Concentrations
Status:
Completed
Trial end date:
2010-12-01
Target enrollment:
Participant gender:
Summary
This study is designed to measure drug concentrations in the blood of healthy volunteers
administered a single dose of ethambutol. Our hypothesis is that volunteers with a body mass
index (BMI) 25-40 kg/m2 will remove ethambutol more quickly from the blood than leaner
volunteers, and those with a BMI > 40 kg/m2 will have even greater clearance than those who
are leaner.
Phase:
Phase 4
Details
Lead Sponsor:
Texas Tech University Health Sciences Center
Collaborators:
National Center for Research Resources (NCRR) University of Texas Southwestern Medical Center