Effect of Vitamin D3 Supplementation on Muscle Mass in ICU Patient

• Status: Unknown status
• Trial end date: 2016-12-01
• Target enrollment: 0
• Participant gender: All

Summary

A randomized double blind placebo control trial study will be conducted in critically ill patients with vitamin D deficiency. Investigator aimed to study the effect of oral vitamin D3 supplementation, compare to placebo, on skeletal muscle mass and body composition.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Mahidol University
• Treatments: Cholecalciferol; Ergocalciferols; Vitamin D; Vitamins

Criteria

Inclusion Criteria:

• Age 18 - 70 years old

• Expected ICU stay ≥ 48 hrs

Exclusion Criteria:

• Participate in other clinical trial

• Contraindication to receive oral or enteral feeding

• Do not resuscitate /imminent death

• Vegetative state, generalize weakness, denervation of leg, both leg amputation

• Hypercalcemia or Hypercalcemia at risk

• Hyperphosphatemia,

• History of nephrolithiasis

• End stage renal disease on renal replacement therapy

• Pregnancy/lactation

• Consent refusal