Effect of Vitamin D3 Supplementation on Arterial and Bone Remodeling in Chronic Kidney Disease Patients
Status:
Completed
Trial end date:
2020-10-01
Target enrollment:
Participant gender:
Summary
To evaluate in patients with chronic kidney disease the impact of two dosages of per os
vitamin D3 supplementation (cholecalciferol) on large arterial stiffness (evaluated non
invasively by pulse wave velocity and high-resolution echotracking system). We will also
study arterial calcification (lateral abdominal radiography and echocardiogram), arterial
remodeling (high-resolution echotracking system), endothelial function (evaluated by a
non-invasive finger biosensor device), and bone remodeling (evaluated by serum biomarkers and
bone mineral density).
Phase:
Phase 4
Details
Lead Sponsor:
Jewish General Hospital
Treatments:
Cholecalciferol Ergocalciferols Vitamin D Vitamins