Effect of Vitamin D and Calcium on Genes in the Colon
Status:
Completed
Trial end date:
2009-05-01
Target enrollment:
Participant gender:
Summary
The researchers are involved in a research program to understand how vitamin D and calcium in
the diet or as supplements may lower the risk of colorectal polyps and cancer. To that end,
the researchers are conducting a study of vitamin D supplementation in which volunteer
subjects are provided a Western style diet for 2 separate 4 week periods at the Rockefeller
University Hospital. During one of these 4 week inpatient periods, subjects receive calcium
supplements and during the other 4 week inpatient period they receive a placebo tablet. The
researchers determine changes within the colon as a result of supplementing the vitamin D in
the presence of high and low calcium. A more detailed description of the study is provided
below.
Phase:
Phase 1
Details
Lead Sponsor:
Rockefeller University
Treatments:
Calcitriol Calcium Calcium, Dietary Cholecalciferol Dihydroxycholecalciferols Ergocalciferols Vitamin D Vitamins