Effect of Vitamin D Repletion on Insulin Resistance and Systemic Inflammation

• Status: Completed
• Trial end date: 2015-09-03
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this research is to study the effects of Vitamin D supplementation on the body's response to insulin (a hormone that controls blood sugar), on inflammation, and on specific cells and processes in fat tissue.

• Phase: Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Albert Einstein College of Medicine; Albert Einstein College of Medicine of Yeshiva University
• Collaborator: National Center for Research Resources (NCRR)
• Treatments: Cholecalciferol; Ergocalciferols; Insulin; Vitamin D; Vitamins

Criteria

Inclusion Criteria:

• Serum 25(OH)D<20ng/ml

• Insulin Resistant based on HOMA-IR score of >3

• Able and willing to provide informed consent

• BMI 20-35

Exclusion Criteria:

• HIV/AIDS

• History of any cancer

• Sarcoidosis

• Alcohol or substance abuse

• Cushing's syndrome

• Primary hyperparathyroidism

• Nephrolithiasis

• Pregnancy or breastfeeding

• Regular visits to a tanning salon

• Hypercalcemia or hypocalcemia

• Untreated or uncontrolled hypertension

• Any chronic illness requiring medication, other than arthritis, hypertension and hyperlipidemia