Effect of Using Azithromycin Versus Placebo With Dexamethasone in Prevention of Post-spinal Nausea and Vomiting.
Status:
Unknown status
Trial end date:
2020-12-01
Target enrollment:
Participant gender:
Summary
Postoperative nausea and vomiting is defined as any nausea, retching, or vomiting occurring
during the first 24-48 h after surgery in inpatients. Postoperative nausea and vomiting is
one of the most common causes of patient dissatisfaction after anesthesia, with reported
incidences of 30% in all post-surgical patients and up to 80% in high-risk patients. In
addition, postoperative nausea and vomiting is regularly rated in preoperative surveys, as
the anesthesia outcome the patient would most like to avoid. While suture dehiscence,
aspiration of gastric contents, esophageal rupture, and other serious complications
associated with postoperative nausea and vomiting are rare, nausea and vomiting is still an
unpleasant and all-too-common postoperative morbidity that can delay patient discharge from
the post-anesthesia care unit and increase unanticipated hospital admissions in outpatients.