Effect of Urine-guided Hydration on Acute Kidney Injury After CRS-HIPEC
Status:
Recruiting
Trial end date:
2025-01-01
Target enrollment:
Participant gender:
Summary
Acute renal injury (AKI) is a common complication after cytoreductive surgery combined with
hyperthermic intraperitoneal chemotherapy (CRS-HIPEC), and is associated with worse outcomes.
Available evidences show that maintaining intraoperative urine output ≥ 200 ml/h by fluid and
furosemide administration may reduce the incidence of AKI in patients undergoing
cardiopulmonary bypass. The investigators hypothesize that, for patients undergoing
CRS-HIPEC, intraoperative urine-volume guided hydration may also reduce the incidence of
postoperative AKI.