Effect of Travoprost 0.004% on Retinal Oximetry in Primary Open Angle Glaucoma
Status:
Completed
Trial end date:
2013-03-01
Target enrollment:
Participant gender:
Summary
Glaucoma is the second leading cause of blindness among seniors in Canada. It is often
associated with an elevated intraocular pressure (IOP), but its exact mechanism is still
largely unknown. Some studies have shown a link between glaucoma and changes in the amount of
oxygen in the veins of the eye. The study aims to compare the amount of oxygen in ocular
veins among three different groups using a spectrophotometer. This instrument is linked to a
camera and can measure the quantity of oxygen in the veins using different characteristics of
the blood inside.
The groups of the study are: patients without glaucoma, patients suspected of glaucoma and
patients newly diagnosed with glaucoma. The drug the investigators are using, Travoprost
0.004%, will only be administered to the groups suspected or diagnosed with glaucoma.
Travoprost 0.004% is already approved for use in Quebec and is part of standard care. Ten
patients will be recruited into each group for a total of 30 patients in this study. All
patients for the suspected or diagnosed groups will be recruited from the Jewish General
Hospital. Subsequently all testing will be done at the École d'optométrie, Université de
Montréal