Effect of Transcutaneous Auricular Vagal Nerve Stimulation on Chronic Constipation
Status:
Recruiting
Trial end date:
2024-02-28
Target enrollment:
Participant gender:
Summary
The worldwide prevalence of chronic constipation (CC) is 15%, and women are more likely to
develop the disease than men. CC have a significant impact on quality of life and increase
the burden of national health insurance. The conventional medication treatments are primarily
symptom-specific and have limited efficacy. Previous small sample study had shown the
therapeutic potential of transcutaneous auricular vagus nerve stimulation (taVNS) for
irritable bowel syndrome with constipation (IBS-C). The aim of this study was to investigate
whether taVNS could improve defecation condition and constipation symptoms in patients with
CC.