Effect of Tranexamic Acid on Blood Loss After High Tibial Osteotomy
Status:
Enrolling by invitation
Trial end date:
2020-12-31
Target enrollment:
Participant gender:
Summary
This study aims to examine whether tranexamic acid has an meaningful clinical effect on blood
loss after high tibial osteotomy. This study design is a double-blind randomized controlled
trial. The patients were randomly assigned to intervention or usual care groups. Intervention
patients receive tranexamic acid 2g for 10 minutes just before surgery. Primary outcome is
hemoglobin level preoperatively, postoperative 1 day, 2 days, 3 days, 2 weeks. Secondary
outcome included hematocrit level, hemovac drainage, total blood loss, need for transfusion,
deep vein thrombosis, Visual Analog Pain Scale, and wound complication.