Effect of Tranexamic Acid on Blood Loss After High Tibial Osteotomy

• Status: Enrolling by invitation
• Trial end date: 2020-12-31
• Target enrollment: 0
• Participant gender: All

Summary

This study aims to examine whether tranexamic acid has an meaningful clinical effect on blood loss after high tibial osteotomy. This study design is a double-blind randomized controlled trial. The patients were randomly assigned to intervention or usual care groups. Intervention patients receive tranexamic acid 2g for 10 minutes just before surgery. Primary outcome is hemoglobin level preoperatively, postoperative 1 day, 2 days, 3 days, 2 weeks. Secondary outcome included hematocrit level, hemovac drainage, total blood loss, need for transfusion, deep vein thrombosis, Visual Analog Pain Scale, and wound complication.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: The Catholic University of Korea
• Treatments: Tranexamic Acid

Criteria

Inclusion Criteria:

• Patients for high tibial osteotomy

• Having medicare insurance

• Accepted patients

Exclusion Criteria:

• History of lower extremity infection or neurologic problems

• Inflammatory arthritis

• Using thrombins

• History of treatment for anemia

• History of thromboembolic event

• Chronic kidney disease