Effect of Topically Administered Levobupivacaine- Fentanyl Versus Levobupivacaine- Dexamethasone Combination in the Control of Pain After Endoscopic Sinus Surgery

• Status: Recruiting
• Trial end date: 2022-03-01
• Target enrollment: 0
• Participant gender: All

Summary

Chronic sinusitis (CRS) is a high incidence disease characterized by pus, nasal obstruction, olfactory disturbance, headache, and other symptoms, lasting for more than 12 weeks, with severe cases having ocular compression and visual impairment, which can cause cranial, eye, and lung complications. Chronic sinusitis is a high-risk disease.

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Assiut University
• Treatments: Dexamethasone; Fentanyl; Levobupivacaine

Criteria

Inclusion Criteria:

• • ASA physical status I-II patients

• scheduled for elective FESS surgery. • Age from 18 to 65 years patients

Exclusion Criteria:

• • Age>18 and<65 years patients,

• Previous history of FESS,

• Patients with sensitivity to anesthetic agents in the study,

• Patients who will do additional septoplasty or turbinate surgery,

• Patients with disturbance of blood coagulation, including pro¬thrombin time (PT)/partial thromboplastin time (PTT) prolon¬gation, purpura, and spontaneous bleeding;