Effect of Topical Brimonidine on Post Cataract Surgery Corneal Edema

• Status: Unknown status
• Trial end date: 2010-01-01
• Target enrollment: 0
• Participant gender: All

Summary

Most patients undergoing cataract surgery suffer from corneal edema after the surgery.

Brimonidine drops are a well known and safe Anti-glaucoma medication. the investigators have made several clinical observations that patients receiving Brimonidine drops had a faster resolution of their corneal edema even if they had normal intra-ocular pressure.

The investigators believe that administering topical Brimonidine to patients with significant post operative corneal edema will hasten the resolution of their corneal edema.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Rabin Medical Center
• Treatments: Brimonidine Tartrate; Maleic acid; Timolol

Criteria

Inclusion Criteria:

• 1 day after uneventful cataract surgery

• corneal edema (grade 2 to 3)

Exclusion Criteria:

• glaucoma

• higher than normal intraocular pressure (>23 mm Hg)

• known sensitivity or contra indication to brimonidine

• known sensitivity or contra indication to timolol

• pre operative corneal or anterior segment disease

• intraoperative complications

• major ocular pathology other than corneal that reduced vision (retinal degeneration, optic neuropathy etc.)

• pregnant women

• children