Effect of Tiotropium + Olodaterol on Breathlessness in COPD Patients
Status:
Completed
Trial end date:
2017-08-14
Target enrollment:
Participant gender:
Summary
The primary objective of the present study is to evaluate the effect of tiotropium +
olodaterol fixed dose combination (FDC) compared to tiotropium monotherapy on the intensity
of breathlessness during the 3min constant speed shuttle test (CSST).
A secondary objective is to explore the relationship between reductions in breathlessness
during the 3min CSST and reductions in breathlessness during activities of everyday living as
measured by the dyspnea domain of the Chronic Respiratory Questionnaire (CRQ) following
bronchodilator therapy.