Effect of Thiamin Supplementation on Thiamin Status in Children With Heart Disease Receiving Diuretic Drugs

• Status: Unknown status
• Trial end date: 2020-07-31
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine effect of thiamin supplementation on thiamin status by measuring thiamin pyrophosphate effect in children with heart disease receiving diuretic drugs.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Mahidol University
• Treatments: Diuretics; Thiamine

Criteria

Inclusion Criteria:

• Children aged 1 month old to 15 years old diagnosed as heart disease

• Receiving diuretic drugs at least 1 month

Exclusion Criteria:

• Receiving thiamin-containing vitamins

• Receiving hemodialysis or peritoneal dialysis

• Having problems of intestinal malabsorption, chronic lung disease, red blood cell abnormality such as thalassemia , abnormal hemoglobin typing, G6PD deficiency

• Receiving thiamin-producing probiotics

• Receiving inotropic drugs

• Severe anemia: Hb < 7 g/dL