Overview

Effect of Tepotinib on Pharmacokinetics (PK) of Cytochrome P450 (CYP) 3A Substrate Midazolam

Status:
Completed
Trial end date:
2018-10-30
Target enrollment:
Participant gender:
Summary
The study will investigate the effect of tepotinib on the PK of the CYP3A substrate midazolam determined from concentrations of midazolam and its main metabolite 1-hydroxymidazolam in healthy participants.
Phase:
Phase 1
Details
Lead Sponsor:
Merck KGaA
Merck KGaA, Darmstadt, Germany
Treatments:
Midazolam
Tepotinib