Effect of Systemic Hypoxia and Hyperoxia on Retinal Oxygen Saturation
Status:
Completed
Trial end date:
2013-01-01
Target enrollment:
Participant gender:
Summary
Adequate perfusion and oxygenation is essential for the function of the inner retina.
Although it is known that oxygen tension is very well autoregulated in the retina, the
physiological mechanisms behind this regulation process are not fully explored. The
development of new instruments for the non-invasive measurement of oxygen tension in retinal
vessels now allows for the more precise investigation of these physiological processes. The
current study seeks to evaluate the retinal oxygen saturation in healthy subjects while
breathing different oxygen mixtures to achieve a hypoxic and a hyperoxic state.