Effect of Supplemental Intake of Omega-3 Polyunsaturated Fatty Acids on the Rate and Complexity of Spontaneously Occurring Ventricular and Supraventricular Arrhythmias in Patients With Implantable Cardioverter Defibrillator (ICD) - A Randomized Clin

• Status: Unknown status
• Trial end date: 2010-06-01
• Target enrollment: 0
• Participant gender: All

Summary

We hypothesize that oral supplementation with omega-3 PUFA will decrease occurrence of arrhythmic events among post-MI, ICD recipients.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Sheba Medical Center

Criteria

Inclusion Criteria:

• post-MI patients.

• Both single and Dual chamber ICD recipient.

• implanted more than 3 months ago.

• Agree to give written informed consent.

Exclusion Criteria:

• Less than 18 years of age.

• ICD implantation as a 'bridge' to heart transplantation.

• Stable antiarrhythmic medication over the last month prior to enrollment.

• Patients taking class I antiarrhythmic medication.

• A projected lifespan less than one year.

• Participation in another trial (during or within 90 days before the study).

• Use of supplemental n-3 fatty acids during the last 3 months.

• Women who are pregnant and of childbearing potential who do not use adequate contraception.

• Patients known to have a history of recent drug or alcohol abuse. 10) History or current intestinal or hepatic disease.