Effect of Supplemental Hydrocortisone During Stress in Prednisolone-induced Adrenal Insufficiency
Status:
Recruiting
Trial end date:
2028-03-01
Target enrollment:
Participant gender:
Summary
In this double-blinded randomised placebo-controlled clinical trial, the aim is to determine
the effect of supplemental hydrocortisone compared with placebo during mild to moderate
physical or mental stress on health related quality of life in patients with polymyalgia
rheumatica (PMR)/giant cell arteritis (GCA) on ongoing low-dose prednisolone diagnosed with
glucocorticoid-induced adrenal insufficiency. The main emphasis is on fatigue (primary
outcome) and daily variation hereof during periods of stress.
Phase:
Phase 4
Details
Lead Sponsor:
Ulla Feldt-Rasmussen
Collaborators:
Aarhus University Hospital Odense University Hospital