Overview

Effect of Statins on Asthma Control in Smokers With Asthma

Status:
Completed
Trial end date:
2009-06-01
Target enrollment:
Participant gender:
Summary
Asthma is a chronic inflammatory condition of the lungs. There is evidence that cigarette smoking can make asthma symptoms worse and that smokers with asthma do not respond as well to standard therapies as non-smokers. Statins are drugs which are already used to lower cholesterol. They have also been shown to have some anti-inflammatory properties. In this trial the investigators will give a randomised group of smokers Atorvastatin and the remaining group a placebo or blank tablet. The investigators will then monitor patients' responses in terms of peak flow data, symptom diaries, questionnaires and breathing tests.
Phase:
Phase 2
Details
Lead Sponsor:
NHS Greater Clyde and Glasgow
Collaborators:
Medical Research Council
University of Glasgow
Treatments:
Atorvastatin
Atorvastatin Calcium