Effect of Smoking Reduction on Endothelial Glucocalyx and Vascular Function

• Status: Active, not recruiting
• Trial end date: 2020-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The integrity of endothelial glucocalyx plays a vital role in vascular permeability and inflammation. Smoking cessation is related with improved vascular function and is a key component of secondary cardiovascular prevention. Pharmacotherapy is a standard component of evidence based smoking cessation treatment. This study was designed to determine the effects medically-aided smoking cessation on glucocalyx thickness and arterial elasticity smoking cessation programs

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of Athens
• Treatments: Nicotine; Varenicline

Criteria

Inclusion Criteria:

• Smokers

Exclusion Criteria:

• Coronary artery disease

• Heart failure

• Diabetes mellitus

• Dyslipidemia