Effect of Single Dose Ketamine and Magnesium on Postoperative Pain in Patients Undergoing Bariatric Surgery

• Status: Completed
• Trial end date: 2019-03-13
• Target enrollment: 0
• Participant gender: All

Summary

Opioid sparing analgesia is extremely important in the post-operative obese population. With more and more obese patients entering the operating room a multi-modal approach to analgesia is crucial. Finding effective alternatives to opioid therapy is the rationale of this proposal. Literature involving ketamine and magnesium in bariatric surgical patients is very sparse.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Milton S. Hershey Medical Center
• Treatments: Ketamine

Criteria

Inclusion Criteria:

1. Subjects undergoing laparoscopic sleeve gastrectomy

2. Consenting adults age 18-80

3. ASA II to ASA III

4. Ability to understand and use a PCA

5. Required to be hospitalized for at least 24 hours post-op

Exclusion Criteria:

1. Patient refusal

2. Chronic opiate use (daily opiate use for >3 months)

3. Chronic Kidney disease (Creatinine>2)

4. Known allergy or adverse effect of ketamine, magnesium or hydromorphone

5. Patients with documented psychiatry (Maniac or MDP) history

6. Patient unable to give informed consent

7. Patient with limited or no English fluency