Effect of Simvastatin on Sepsis and Febrile Neutropenia in Patients With Acute Lymphoblastic Leukemia
Status:
Not yet recruiting
Trial end date:
2023-06-23
Target enrollment:
Participant gender:
Summary
In general, the percentage of complete remissions is 85 - 90 % for acute lymphoid leukemia
(ALL). In developing countries, percentages are lower secondary to higher sepsis-related
mortality. Although the effect of statins on inflammatory response associated with sepsis has
been demonstrated, including an effect on bacterial proliferation in patients with a state of
immunosuppression, their effect has not been demonstrated so far in patients with
hemato-oncological cancer.