Effect of Short Term Aliskiren Treatment in Kidney Transplant Patients
Status:
Terminated
Trial end date:
2012-01-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to evaluate the effect of a short-term aliskiren treatment on
kidney metabolism in patients at high risk for developing kidney dysfunction (i.e. kidney
transplanted patients). The study is aimed at evaluating if any effect on kidney metabolism
[using proton MR Spectroscopy(1H-MRS)] can be detected following a 6 months treatment with
aliskiren regardless of its anti-hypertensive role. 1H-MRS can record a larger number of
chemical species (up to 40) in the kidney, and monitor changes according to the pathologic
state and health of the transplanted kidney.