Effect of SRT2379 on Endotoxin-Induced Inflammation
Status:
Completed
Trial end date:
2011-04-26
Target enrollment:
Participant gender:
Summary
SRT2379 is a potent small molecule activator of SIRT1 that has been found to inhibit systemic
inflammation induced by intravenous injection of lipopolysaccharide (LPS) in mice. The
objective of this study is to test if SRT2379 may be a novel compound for the treatment of
inflammatory disorders in man.