Effect of S-ketamine Anesthetic on Inflammatory Response in Septic Patients Undergoing Abdominal Surgery
Status:
Recruiting
Trial end date:
2023-10-30
Target enrollment:
Participant gender:
Summary
This study is a randomized, double-blinded, controlled design. In this study, low doses of
S-ketamine were selected for surgury treatment in septic patients under general anesthesia ,
Meanwhile, activity of HO-1 protein , oxidative stress and inflammatory markers in serum are
measured to evaluating the effects of S-ketamine Anesthetic on inflammatory response in
septic patients undergoing abdominal surgury. In addition,It is very necessary to make use of
the advantages of low-dose S-ketamine in anti-inflammation, and avoid the side effects of
mental symptoms, so as to guide the new direction of perioperative clinical application of
S-ketamine.