Overview

Effect of Repeated Oral Doses of Avacopan on the Pharmacokinetics (PK) of a Single Dose of Simvastatin

Status:
COMPLETED
Trial end date:
2022-08-11
Target enrollment:
Participant gender:
Summary
The primary objective of this clinical study is to evaluate the effect of repeated oral doses of avacopan (30 mg and 60 mg twice daily approximately 12 hours apart \[BID\]) given under fed conditions on the PK of a single dose of simvastatin (40 mg) in healthy volunteers.
Phase:
PHASE1
Details
Lead Sponsor:
Amgen
Treatments:
avacopan
Simvastatin