Overview

Effect of Repeated Dosing of Naproxcinod on Renal Hemodynamic and on Sodium Balance in Healthy Volunteers Before and After a Single Dose of Furosemide

Status:
Completed

Trial end date:
2009-04-01

Target enrollment:

Participant gender:

Summary

This phase 1 study is an 8-day treatment period, randomized, controlled, double-blind, 3 parallel-groups, monocentric study. The primary objective is to evaluate the effect of naproxcinod on the renal function when co-administered with furosemide in comparison to naproxen and placebo.

Phase:

Phase 1

Details

Lead Sponsor:

NicOx

Treatments:

Furosemide
Naproxen
Naproxen-n-butyl nitrate