Effect of Remifentanil on Electroencephalographic BAR Index During Propofol Anaesthesia

• Status: Completed
• Trial end date: 2007-10-01
• Target enrollment: 0
• Participant gender: All

Summary

Current cortical EEG based depth of anaesthesia monitors do not accurately reflect the effect of opioid drugs. We have developed a new theoretically-based method of analysing the EEG. Our hypothesis is that this new method will more accurately predict depth of anaesthesia than the Bispectral Index (BIS) monitor in patients having elective surgery.

• Phase: Phase 1
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Melbourne Health
• Collaborator: Biopharmica Limited
• Treatments: Propofol; Remifentanil

Criteria

Inclusion Criteria:

• Male and female patients, aged 18-60 years, of ASA physical status 1-3, presenting for elective surgery under general anaesthesia

Exclusion Criteria:

• Inadequate English comprehension due to a language barrier, cognitive deficit or intellectual disability

• Epilepsy or other EEG abnormality

• Prescription or illicit drugs known to affect the EEG