Effect of Propofol on Renal Injury in Patients Undergoing Valvular Heart Surgery
Status:
Completed
Trial end date:
2012-05-01
Target enrollment:
Participant gender:
Summary
Ischemia/reperfusion (I/R)-induced acute kidney injury is a serious complication affecting
patient outcome following cardiovascular surgeries. Propofol, an intravenously administered
anesthetic with antioxidant properties, protects organs from I/R injury. This study aimed to
investigate the ability of propofol to protect kidneys against I/R injury in the patients
undergoing valvular heart surgery.