Effect of Propofol on Cardioprotective Role of Remote Ischemic Preconditioning (RIPC)
Status:
Completed
Trial end date:
2018-02-07
Target enrollment:
Participant gender:
Summary
This study involves research using human subjects (cardiac surgical patients) to evaluate the
effect of remote ischemic preconditioning (RIPC) on cardioprotective outcomes. RIPC applied
to upper or lower extremities has been shown cardioprotective role by lowering release of
cardiac troponin in patients with cardiac diseases. However, it is not clear whether
anesthetics, such as propofol or sevoflurane, may impair the cardioprotective effect of RIPC
in cardiac surgical patients. Therefore, the purpose of the study is to compare the effects
of anesthetics on cardioprotection of RIPC in patients undergoing cardiac surgery.