Overview

Effect of Propofol and Sevoflurane on Lactate During Anesthesia for Pediatric Heart Catheterisation

Status:
Completed
Trial end date:
2010-08-01
Target enrollment:
0
Participant gender:
All
Summary
Propofol is routinely used for general anesthesia during pediatric heart catheterisation. Propofol infusion syndrome (PRIS) is a rare, but often fatal complication mainly defined by bradycardia with progress to asystolia during propofol infusion. Metabolic acidosis is regarded as an early warning sign of PRIS. In this study the effect of propofol and sevoflurane on serum base excess, pH and lactate are examined during pediatric heart catheterisation.
Phase:
N/A
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
University Hospital Schleswig-Holstein
University of Schleswig-Holstein
Treatments:
Anesthetics
Propofol
Sevoflurane
Criteria
Inclusion Criteria:

- Indication for heart catheterization under general anesthesia

Exclusion Criteria:

- Participation in another study

- Preexisting metabolic acidosis

- Contraindication against Propofol