Effect of Prophylactic Tranexamic Acid on Bleeding Outcomes in Women Undergoing Dilation and Evacuation
Status:
Not yet recruiting
Trial end date:
2023-01-01
Target enrollment:
Participant gender:
Summary
Prophylactic tranexamic acid has shown been shown to reduce maternal mortality from
postpartum hemorrhage with no adverse effects, but has not been studied to reduce bleeding
complications with dilation and evacuation (D&E). We propose a randomized, double-blinded,
placebo-controlled pilot study to determine whether routine use of intravenous (IV)
tranexamic acid will decrease the need for interventions to control bleeding at the time of
D&E at 16 to 24 weeks gestation.