Effect of Prophylactic Fibrinogen Concentrate In Scoliosis Surgery
Status:
Not yet recruiting
Trial end date:
2023-02-28
Target enrollment:
Participant gender:
Summary
EFISS is a prospective, randomized, placebo-controlled trial testing the feasibility, safety
and efficacy of prophylactic administration of fibrinogen in paediatric spinal surgery. The
study is monocentric and will be conducted in University Hospital Brno, Czech Republic. This
is a pilot study in which the primary objective will be to evaluate the feasibility of a
clinical trial in 32 selected patients undergoing scoliosis surgery. Participants will be
randomized into study groups in a 1:1 allocation ratio and followed up for 28 days after
surgery. The expected duration of this clinical trial is 8 months.