Overview

Effect of Prolotherapy in Knee Osteoarthritis.

Status:
Recruiting

Trial end date:
2021-03-30

Target enrollment:
0

Participant gender:
All

Summary

Patients with primary knee osteoarthritis will be included in the study, plain X-ray for the affected knee, followed by musculoskeletal ultrasound assessment will be done. The intervention: intra-articular injection and extra-articular injections of 25% dextrose. Follow up will be done at 24 weeks after the last injection both clinically and ultrasonographically . Aim: Determine whether prolotherapy improves pain. stiffness and function of symptomatic knee osteoarthritis and determine ultrasonographic changes before and after prolotherapy.

Phase:

N/A

Accepts Healthy Volunteers?

Details

Lead Sponsor:

University of Alexandria

Criteria

Inclusion Criteria:

- Moderate and moderate to severe primary Knee osteoarthritis (KL grade II and III)

- consent obtained

Exclusion Criteria:

- Severe Knee osteoarthritis (KL grade IV)

- Causes of 2ry osteoarthritis: other rheumatological, metabolic and inflammatory joint
diseases.

- received oral or systemic steroids 1 month prior to the procedure

- received intra-articular steroids or hyaluronic acid 1 month prior to the procedure

- BMI >45Kg/m2