Effect of Progesterone on Testosterone Concentrations and Breast Development in Transwomen
Status:
Recruiting
Trial end date:
2023-12-31
Target enrollment:
Participant gender:
Summary
- Purpose. The purpose of this research is study the effect of progesterone therapy on
testosterone levels in transwomen who are currently on gender affirming treatment with
estradiol.
- Duration. It is expected that participation will last for 6 months (24 weeks).
- Study Procedures. Participants will be asked to sign an informed consent, complete a
medical history, have a physical exam conducted, have a fasting blood sample taken and
asked to take a study drug once daily.
- Risks. Some of the foreseeable risks or discomforts include temporary discomfort,
bleeding, bruising and/or swelling in the arm from blood draw. There are no known direct
risks with the use of Progesterone in Transwomen for gender affirming therapy.
- Benefits. Some of the possible benefits that may be expected include increase in fat
mass, increase in breast size/fullness, decrease in masculine hair patterns.