Effect of Prevacid on Prostaglandin Levels in Patient With Stress Ulcer

• Status: Completed
• Trial end date: 2007-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to measure the prostaglandin levels in patients with stress ulcer and the effect of Prevacid on prostaglandin levels in patients with stress ulcer.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Emory University
• Collaborator: TAP Pharmaceutical Products Inc.
• Treatments: Dexlansoprazole; Lansoprazole

Criteria

Inclusion Criteria:

• Patients in ICU with documented gastric stress ulcer by endoscopic examination, including patients with H. Pylori infection;

• Patients have no known ulcer within 8 weeks prior to be admitted to ICU;

• Patients not on any PPI for 4 weeks prior to the study;

• Patients or family be consented for the study.

Exclusion Criteria:

• Patients have gastric ulcer within 8 weeks prior to be admitted to ICU;

• Patients have gastric cancer confirmed by pathology;

• Patients on one of the PPIs already;

• Patients on any of the Non-steroidal Antiinflammatory Drugs.