Effect of Preoperative Topical Ketorolac on Aqueous Cytokine Levels and Macular Thickness in Cataract Surgery Patients

• Status: Completed
• Trial end date: 2015-06-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine whether there is a relationship between inflammatory cytokines in the aqueous of the eye and thickness of the macula after treatment of topical ketorolac for patients undergoing cataract surgery.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of Malaya
• Treatments: Ketorolac; Ketorolac Tromethamine; Ophthalmic Solutions; Pharmaceutical Solutions

Criteria

Inclusion Criteria:

Diabetic patient group

1. Type 2 diabetes mellitus with no diabetic retinopathy

2. If with co-morbid, controlled hypertension with no hypertensive crisis in recent six months

3. Listed for phacoemulsification cataract surgery

Non diabetic patient group

1. No history of diabetes

2. If with co-morbid, controlled hypertension with no hypertensive crisis in recent six months

3. Listed for phacoemulsification cataract surgery

Exclusion Criteria:

1. Smoker

2. Presence of immune disease, local or systemic inflammation

3. Presence of retinal diseases, glaucoma

4. Previous surgical procedure on the eye

5. Intra-operative complications