Overview

Effect of Pregabalin on Post Operative Pain in Abdominal Hysterectomy Under Spinal Anesthesia With Intrathecal Morphine

Status:
Completed

Trial end date:
2016-08-01

Target enrollment:
0

Participant gender:
All

Summary

This study aims to compare the effect of pre-operative oral pregabalin on post operative morphine consumption after abdominal hysterectomy with/without salpingo-oophorectomy.

Phase:

Phase 4

Accepts Healthy Volunteers?

Details

Lead Sponsor:

Mahidol University

Treatments:

Anesthetics
Morphine
Pregabalin

Criteria

Inclusion Criteria:

1. ASA classification 1-2 undergoing abdominal hysterectomy with/without
salpingo-oophorectomy under spinal anesthesia with intrathecal morphine

2. Patient can use patient-controlled analgesia (IV PCA)

Exclusion Criteria:

1. History of drug allergy to gabapentinoid and related drug

2. History of regular analgesic drug use, psychiatric drug usage, drug abuse, alcohol
addiction or chronic pain patient

3. Renal disease (Creatinine Clearance < 60), Liver disease, Seizure disorder and
Psychiatric disorder