Effect of Pineapple Juice on the Pharmacokinetics of Celecoxib and Montelukast in Humans

• Status: Completed
• Trial end date: 2019-12-01
• Target enrollment: 0
• Participant gender: Male

Summary

Pineapple (Ananas comosus) is a tropical fruit that is rich in antioxidents, enzymes and vitamins. It is used worldwide due to their anti-inflammatory and analgesic properties. The effect of pineapple Juice on the Pharmacokinetics of celecoxib and montelukast in Humans was studied.

• Phase: Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Damanhour University
• Treatments: Celecoxib; Montelukast

Criteria

Inclusion Criteria:

• Healthy subjects (body mass index between 21 to 25 kg/m2).

Exclusion Criteria:

• Smokers.

• Drug abuse.

• Abnormal level of kidney or liver functions.