Effect of Photodynamic Therapy on Soft Tissue Healing After Tooth Extraction at Sites of Periodontal Infection

• Status: Not yet recruiting
• Trial end date: 2024-06-01
• Target enrollment: 0
• Participant gender: All

Summary

Main Purpose: To evaluate the effect of photodynamic therapy on soft tissue healing after tooth extraction at periodontal infection site, and to compare the effect on pain degree and bone tissue remodeling after tooth extraction.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: The Dental Hospital of Zhejiang University School of Medicine

Criteria

Inclusion Criteria:

• Age range from 18 to 65 years old;

• Patients with extensive periodontitis of the whole mouth;

• There was a deep periodontal pocket with PD≥5mm and at least one adjacent tooth at the extraction site;

• Periodontitis was controlled, and the extraction site and adjacent teeth were not in the acute inflammation or infection stage;

• The extraction site has a hopeless prognosis or no preservation value, and it is the first and second molars or maxillary wisdom teeth that erupt in a positive position

Exclusion Criteria:

• pregnant and lactating women;

• patients with systemic diseases that may affect the ability of postoperative healing (such as patients with radiotherapy and chemotherapy, history of hematological diseases, and uncontrolled disease) Diabetes mellitus, etc.);

• long-term use of drugs known to affect bone metabolism or mucosal healing such as bisphosphonates and non-steroidal anti-inflammatory drugs;

• smoking > 10 cigarettes per day;

• root breakage or gingival tear occurred during tooth extraction.