Effect of Perioperative Tranexamic Acid on Blood Loss During Management of Maxillofacial Trauma

• Status: Not yet recruiting
• Trial end date: 2021-12-15
• Target enrollment: 0
• Participant gender: All

Summary

This is a prospective, randomized, double-blind study investigating whether intravenous tranexamic acid has any effect on blood loss during maxillofacial trauma surgery, or the subsequent postoperative sequelae. Intraoperative bleeding and postoperative ecchymosis and edema are objectively rated and complications are noted.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: College of Medical Sciences Teaching Hospital. Nepal
• Treatments: Tranexamic Acid

Criteria

Inclusion Criteria:

• Patients undergoing ORIF under GA for Maxillofacial fractures

• Patients between with ages of 16-65

• No cardiac comorbidities (hypertension, congenital heart malformation)

• No known coagulopathy

• No regular prescription medication altering normal blood coagulation (NSAIDs, other anticoagulants)

• ASA I and II patients

Exclusion Criteria:

• Patients younger than 16 and older than 65

• Patients with known coagulopathy

• Patients with cardiac comorbidities

• Patients with a family history of bleeding disorders

• ASA III or higher