Effect of Pentoxifylline and Zinc Co-administration in Patients With Oligoasthenoteratozoospermia

• Status: Not yet recruiting
• Trial end date: 2022-05-28
• Target enrollment: 0
• Participant gender: Male

Summary

The aim of this study is to investigate the impact of co-administration of Pentoxifylline and Zinc sulfate on oxidative stress, apoptosis, and inflammation, sperm capacitation and parameters in infertile men.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Arak University of Medical Sciences
• Treatments: Pentoxifylline; Zinc; Zinc Sulfate

Criteria

Inclusion Criteria:

• Idiopathic infertile men

• have had at least one year of unprotected intercourse infertility

• Sperm parameters abnormality

Exclusion Criteria:

• Men with varicocele

• Hypersensitivity to pentoxifylline & zinc,

• pelvic organic pathologies

• congenital adrenal hyperplasia

• thyroid dysfunction

• Cushing's syndrome

• hyper prolactinemia

• androgen secreting neoplasia

• diabetes mellitus

• consumption of medications affecting carbohydrate metabolism

• severe hepatic

• pancreatitis

• kidney diseases

• gallbladder diseases

• Patients with alcohol consumption

• Patients who use cigarettes and drugs