Effect of Palatable Lidocaine Gel on Gag Reflex for Patients Undergoing Upper Gastrointestinal Endoscopy
Status:
Completed
Trial end date:
2020-06-01
Target enrollment:
Participant gender:
Summary
- The development of upper gastrointestinal endoscopy (UGIE) has greatly expanded the
diagnostic and therapeutic capabilities of gastroenterologists. The patient's tolerance
to procedure and endoscopist's satisfaction increase when sedation is used along with
topical pharyngeal anesthesia.
- Numerous agents are available for moderate sedation in endoscopy such as propofol,
midazolam, ketamine, fentanyl and dexmedetomidine, the choice of a particular sedative
agent depends on its availability, cost and experience of the endoscopist and patient
with that sedative agent. However, these i.v. anesthetics may be associated with
complications especially in elderly patients or in those with other comorbidities, as
apnea, hypoxia, hypotension, and paradoxical agitation, in which the patient becomes
agitated rather than sleepy from the sedation, leading to increased morbidity and the
duration of the patient's hospitalization.
- Local application of lidocaine to the oral cavity and the oropharynx, will attenuate or
even abolish the gag reflex increasing the patient's comfort thus decreasing the dose of
i.v. anesthetics with their potential complications.
- Up to our knowledge, there is no study done to evaluate the effect of palatable
lidocaine gel versus I .v dexmedetomidine on the incidence of gag reflex and total
propofol consumption during elective upper gastrointestinal endoscopy.