Effect of PTH(1-34) Treatment on Fracture Healing in Vivo

• Status: Withdrawn
• Trial end date: 2010-09-01
• Target enrollment: 0
• Participant gender: Female

Summary

The purpose of the study is to investigate, whether PTH(1-34) is able to promote fracture healing in postmenopausal women with fractures of the hip or shoulder.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Glostrup University Hospital, Copenhagen
• Collaborator: The Danish Medical Research Council
• Treatments: Teriparatide

Criteria

Inclusion Criteria:

• Acute new osteoporotic trochanteric or collum chirurgicum fracture

• Postmenopause

Exclusion Criteria:

• Calcium metabolic disease other than osteoporosis

• Diseases known to affect calcium homeostasis

• Dementia

• Hypersensitivity to drug or other components of medication

• pre-existing hypercalcemia

• Decreased kidney function

• Increased alkaline phosphatase

• Prior external radiation therapy or brachytherapy of the skeleton

• Skeletal malignancies or bone metastases

• Alcohol and/or drug abuse

• Systemic treatment with corticosteroids within the last four weeks

• Non-cooperating patients

• Patients who do not speak and understand the danish language