Effect of P-glycoprotein Inhibition on Lenalidomide Pharmacokinetics in Healthy Males
Status:
Completed
Trial end date:
2013-01-01
Target enrollment:
Participant gender:
Summary
To find out if the blood level of lenalidomide can be changed when a drug that prevents
p-glycoprotein (a protein naturally present in the body that helps carry substances across
cell membranes that is found in many parts of the body like the intestines, liver, and
kidneys) from working (called a P-gp inhibitor) when taken together with lenalidomide. The
study is also trying to find out if blood level of temsirolimus can be changed when a subject
takes lenalidomide together with temsirolimus.