Effect of Oral Isotretinoin on The Level of SerumYKL40 in Acne Vulgaris Patients

• Status: Active, not recruiting
• Trial end date: 2022-07-31
• Target enrollment: 0
• Participant gender: All

Summary

The aim of the study is to evaluate the effect of oral isotretinoin on SerumYKL40 in acne vulgaris patients.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Alshimaa Abbas Mohamed Ebrahim
• Treatments: Isotretinoin

Criteria

Inclusion Criteria:

1. Healthy persons of both sexes with moderate and severe acne.

2. Age above 14 years.

Exclusion Criteria:

1. Pregnant and lactating women, immunocompromised patients.

2. History of chronic liver disease, hyperlipidemia, non-inflammatory acne conditions, , history of neurologic disorders, history of neoplastic disorders, and history of cardiac disease.

3. History of systemic acne treatment for at least 4 weeks prior to inclusion and no topical treatments for at least 2 weeks.

4. Cases with known hypersensitivity reaction to isotretinoin.