Overview

Effect of Oral 5-HTP Intake on Urinary 5-HIAA Excretion

Status:
Terminated
Trial end date:
2005-09-01
Target enrollment:
0
Participant gender:
All
Summary
This is a research study looking at the effect of 5-Hydroxy Tryptophan (5-HTP) on urine excretion of 5-Hydroxyindolacetic acid (5-HIAA). 5-HTP is a common over the counter product that is sold in natural food stores and via the Internet. Increased levels of 5-HIAA in the urine can be found in a specific type of cancer, called carcinoid tumor. This study will examine the effect of oral 5-HTP intake on 5-HIAA excretion. Understanding this effect may help to determine which tests should be done in a patient with increased 5-HIAA excretion who's also taking 5-HTP.
Phase:
Phase 3
Accepts Healthy Volunteers?
Accepts Healthy Volunteers
Details
Lead Sponsor:
University of Western Ontario, Canada
Treatments:
Serotonin
Criteria
Inclusion Criteria:

- 18 years and older

- in good health

Exclusion Criteria:

- Pregnancy

- Intake of drugs that affect 5-HIAA excretion in urine

- Anti-depressants

- Participation in other studies