Effect of Omega -3 Fatty Acids Supplements and Plant Sterol Enriched Food in Dyslipidemic Adults
Status:
Completed
Trial end date:
2007-03-01
Target enrollment:
Participant gender:
Summary
The incidence of chronic degenerative diseases, especially cardiovascular disease (CVD), is
high world over and especially in India. High blood cholesterol and triglyceride levels are
known to be important risk factors for CVD. There is a strong body of evidence for the
beneficial effects of plant sterols on blood total and LDL-cholesterol and omega-3 fatty
acids from fish on blood triglycerides. However, the combined benefits of consuming both
plant sterols and omega-3 fatty acids from fish oil on blood cholesterol and triglycerides
has not been investigated previously, except in one study where the methodology used was not
the most appropriate for testing such a combination. In addition, most studies on plant
sterol efficacy realised so far were done in Western countries. The present study will
investigate the efficacy of plant sterols and omega-3 fatty acids from fish oil on improving
the cardiovascular risk profile of Indian adults with dyslipidemia.
It is expected that, after 4 weeks of intervention, men consuming both plant sterols and
omega-3 fatty acids from fish oil will have a lower cardiovascular risk profile than men
receiving only plant sterols or only fish oil or none of these dietary supplements.