Effect of Neural Constraints on Movement in Stroke
Status:
RECRUITING
Trial end date:
2029-07-31
Target enrollment:
Participant gender:
Summary
This study investigates the effects of Tizanidine on the voluntary movement controls of the arms of participants who have had a stroke and have not had a stroke by measuring medication-induced changes in upper extremity kinematics, pupillometry, and brain activity. Tizanidine is approved by the U.S. Food and Drug Administration. Understanding how different areas of the brain are involved in movement impairments may help rehabilitation efforts and assist in restoring healthy movement in individuals who have had a stroke.
Phase:
EARLY_PHASE1
Details
Lead Sponsor:
Northwestern University
Collaborator:
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)